Basal Cell Carcinoma vs. Squamous Cell Carcinoma

BCC is the most common type of skin cancer and occurs in sun-exposed areas. SCC may occur on any skin surface, but is also most commonly seen on sun-exposed areas.

SCC may arise from actinic keratoses and sites of chronic wounds or scarring. SCC is more common and more aggressive in immunosuppressed or transplant patients.

BCC presents as a “pearly” papule or nodule that grows slowly. The lesion tends to develop a shiny appearance with telangiectasias and an umbilicated center or ulcer. The appearance of SCC is variable. It is usually characterized as a hyperkeratotic lesion with crusting and ulceration.

For both BCC and SCC, biopsy is indicated for diagnosis. Lesions are typically treated with surgical excision, cryotherapy, electrodessication or topical chemotherapy.