CREST syndrome (limited cutaneous systemic sclerosis):
Calcinosis: calcium deposits in the skin and tissues.
Raynaud’s phenomenon: an exaggerated vascular response to cold temperature or emotional stress which may manifest as white-blue-red transitions in skin color.
Esophageal dysmotility: contractions in the esophagus become irregular or absent, causing dysphagia, heartburn, or atypical chest pain
Sclerodactyly: thickening and tightening of the skin, which makes it harder to bend or straighten the fingers. May also occur on the face.
Telangiectasias: dilated blood vessels which appear as red spots on the face and other areas.