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Hematology and Oncology

Hodgkin Lymphoma

Hodgkin lymphoma (HL) is a clonal B-cell malignancy that resides predominantly in the lymphatic system. HL tends to develop within a single lymph node region and spreads in an orderly fashion to adjacent lymph nodes. A defining characteristic of HL is the presence of...

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Medulloblastoma

Medulloblastoma is the most common type of malignant brain tumor in childhood. It is an aggressive solid tumor malignancy that develops in the posterior fossa, which contains the brain stem and cerebellum. Boys are affected more frequently than girls, with cases...

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Chronic Myelogenous Leukemia

Chronic Myelogenous Leukemia (CML) is a myeloproliferative disease characterized by proliferation of myeloid cells capable of differentiation. CML is caused by a reciprocal translocation t(9;22), in which a piece of chromosome 9 containing the ABL1...

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Acute Myelogenous Leukemia

Acute Myelogenous Leukemia (AML) is the most common acute leukemia in adults. Most patients are over 65 years of age and the incidence increases with advanced age. AML is characterized by the sludging of blasts in the microvasculature due to leukostasis...

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Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia (ALL) is the most common cancer in children, but it can also occur in adults of all ages. There is a bimodal distribution, with peaks at 3-7 years and 65 years of age. The clinical presentation of ALL is nonspecific: fever,...

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Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia (CLL) is the monoclonal proliferation of malignant B lymphocytes. It is the most common adult leukemia in Western countries, accounting for 30% of all cases in the United States. CLL typically affects adults greater than 65...

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